Propofol

The issue with propofol is that it can make the patient's brain forget to breathe - Benjamin C Wedro MD

Propofol
Propofol

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Michael Jackson's Death: propofol (Diprivan) FAQ

Propofol is a drug that was on trial as causing the death of the music icon. Guilt by association: not the doctor who administered the drug but for the propofol itself. Here is a perfectly fine anesthetic agent, minding its own business, being scrutinized just because it was in the wrong place at the wrong time.

Actually, propofol (Diprivan) should never be carried by a doctor making a house call. It's meant for hospital use in the intensive care unit or the operating room, for patients who are intubated and on a ventilator. It's meant for the emergency room when people have to be sedated for a few seconds to undergo a painful procedure such as cardiac shock, or to fix a joint dislocation.…

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 Michael Jackson's Death: propofol (Diprivan) FAQ

Propofol is a drug that was on trial as causing the death of the music icon. Guilt by association: not the doctor who administered the drug but for the propofol itself. Here is a perfectly fine anesthetic agent, minding its own business, being scrutinized just because it was in the wrong place at the wrong time.

DailyMed

DIPRIVAN Injectable Emulsion is an intravenous sedative-hypnotic agent for use in the induction and maintenance of anesthesia or sedation. Intravenous injection of a therapeutic dose of propofol induces hypnosis, with minimal excitation, usually within 40 seconds from the start of injection (the time for one arm-brain circulation). As with other rapidly acting intravenous anesthetic agents, the half-time of the blood-brain equilibration is approximately 1 to 3 minutes, accounting for the rate of induction of anesthesia. The mechanism of action, like all general anesthetics, is poorly understood. However, propofol is thought to produce its sedative/anesthetic effects by the positive modulation of the inhibitory function of the neurotransmitter GABA through the ligand-gated GABAA receptors.

DEA

User Population: Propofol is mostly abused by health care staff including anesthetists, practitioners, nurses and technicians. Control Status: Propofol is not scheduled under the Controlled Substances Act.

PDR

Intravenous, nonbarbiturate anesthetic. Used for induction and maintenance of anesthesia and sedation of mechanically ventilated adult patients in the intensive care unit. Induces anesthesia as quickly as thiopental with more rapid emergence.

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