Before you even consider participating in a diabetes clinical trial, you need to know the basics of a clinical trial to make an informed decision whether you want to participate at all. Here we spell out the A B C D E of clinical trials and what it all means...
Romero is one of a handful of people in the world participating in a new clinical trial that’s studying whether pancreatic progenitor cells, transplanted into a person with type 1 diabetes, can become cells that produce insulin naturally—effectively curing the disease. Developed by ViaCyte, the trial is available at three sites in North America, including University of Minnesota Health.
Diabetes has become an epidemic, with over 422 million people affected worldwide sentenced to lifelong medication. Science is striving to find a cure to this chronic disease, but how close are we?
Kinyatta is, in her own words, “a helper.” That helping spirit shines through in her work as an instructional assistant co-teaching the first grade. It also shows in her long-standing participation—for 15 years and counting—in the SEARCH for Diabetes in Youth study, a unique research study committed to improving the quality of life of children and young adults with diabetes.
People participate in clinical research for many reasons: to help others, to have the opportunity to try a new treatment or prevention strategy, to have the additional care provided by research staff, and to advance scientific progress.
Participating in a research study can be overwhelming and intimidating. Here are our Top 10 Reasons to Participate in a research study and how YOU can make a difference.
Advances in treatments and technology for type 1 diabetes are only made possible by the willingness of volunteers to take part in clinical research. Research volunteers, whether patients or healthy subjects, play a vital role in clinical research. Without research volunteers, clinical trials for exciting and cutting-edge new treatments cannot go ahead.
A century ago, doctors and scientists had no universally established methods for determining how effective medical treatments were. While modern, controlled research trials date back as far as 1747, a major milestone came in 1946 with the first randomized "curative" clinical trial.
Over the years, a number of landmark clinical studies have been published in the diabetes space and shaped how we treat the disease today. Here are 10 studies involving diabetes every pharmacist should know:
In this article, we have summarised 4 clinical trials for Type 1 Diabetes. We explain the scientific reasoning behind each treatment and what the current findings are (including any potential side effects).
This chapter begins with a discussion of government-sponsored diabetes clinical trials. Next, a clinical research network—TrialNet—is described, along with the ways in which it conducts trials in diabetes.
We list current opportunities for getting involved here. The list is provided for information purposes only and should not be treated as advice or a recommendation for participation in any of the studies.
Pittas says clinical trials are most beneficial to people not involved in the study. "We do not know whether a specific participant will benefit from the intervention," he says. "Mostly, it's a benefit to others in the future based on the knowledge [that] is gained from the study."
Kris, from Middlesbrough, talks about his experience of being diagnosed as an adult, on 23 March 2012, and his involvement with type 1 diabetes research.
Match to clinical trials in 60 seconds.
TrialNet is a network of 18 Clinical Centers working in cooperation with screening sites throughout the United States, Canada, Finland, United Kingdom, Italy, Germany, Australia, and New Zealand. This network is dedicated to the study, prevention, and early treatment of type 1 diabetes
The Diabetes Trials Unit (DTU), founded in 1985 by Professor Rury Holman, specialises in performing diabetes-related national and multinational mega trials in partnership with the NHS, NIH, MRC, BHF, DUK, academic institutions and industry. The DTU also undertakes major modelling and statistical programmes to utilise fully the data available from its many studies, with a particular emphasis on modelling diabetes and cardiovascular disease processes.
ResearchMatch has a simple goal — to bring together two groups of people who are looking for one another: (1) people who are trying to find research studies, and (2) researchers who are looking for people to participate in their studies. It is a free and secure registry that has been developed by major academic institutions across the country who want to involve you in the mission of helping today’s studies make a real difference for everyone’s health in the future.
The All of Us Research Program is a historic effort to gather data from one million or more people living in the United States to accelerate research and improve health. By taking into account individual differences in lifestyle, environment, and biology, researchers will uncover paths toward delivering precision medicine.
We provide information services used by patients, pharmaceutical, biotechnology and medical device companies, CROs and research centers involved in clinical research around the world.
Welcome to Clinical Connection, the leading source for clinical trials information and notifications.
ClinicalTrials.gov is a Web-based resource that provides patients, their family members, health care professionals, researchers, and the public with easy access to information on publicly and privately supported clinical studies on a wide range of diseases and conditions. The Web site is maintained by the National Library of Medicine (NLM) at the National Institutes of Health (NIH).
D2d is a large-scale clinical trial to investigate if vitamin D supplementation helps prevent or delay type 2 diabetes in adults who are at high risk for diabetes (pre-diabetes).
The Register also provides information about older paediatric trials covered by an EU marketing authorisation.
The Register enables you to search for information in the EudraCT database External link. This is the database used by national medicines regulators for data related to clinical trial protocols. The data on the results of these trials are entered into the database by the sponsors themselves and are published in this Register once the sponsors have validated the data.
The Glycemia Reduction Approaches in Diabetes: A Comparative
Effectiveness Study (GRADE) is a long-term study of different
treatments for type 2 diabetes.
Our site is here to help you find out about health and social care research that is taking place across the UK.
You can find out what 'clinical trials' and 'health and social care research' involves as well as finding out about studies that are happening right now into any condition or disease area.