Sartan Recalls

Another Blood Pressure Med Recall For Cancer Concerns, What You Should Do

Panicking ain't good for your blood pressure, even if it is at the disco. Even though a chemical is a carcinogen, doesn't mean that ingesting small amounts over a short period of time will give you cancer. Plus, these recalls only have affected certain blood pressure medications. None of these recalls were "total recalls." Not all brands and batches of losartan, valsartan, and irbesartan were involved. There are many other types and classes of blood pressure medications available.

Blood Pressure Medicine Is Recalled

The safety of imported drugs has long been debated. The F.D.A. said it would continue to investigate the levels of NDMA in the recalled products, determine the possible effect on patients who have been taking them, and assess what measures can be taken to reduce or eliminate the impurity from future batches.

Cancer Fears Have Triggered Blood Pressure Drug Recalls for Months. Now Patients Are 'Leery'

The agency says it continues to investigate how these substances got into ARB drug supplies, and is working to stem the flow of potentially tainted pharmaceuticals from overseas manufacturers. Many of the affected ARBs came from producers in China and India, according to FDA recall notices, and the FDA warned one Chinese manufacturer about “significant” production issues last year.

Valsartan and Losartan Recalled Due to Risk of Causing Cancer

Valsartan and Losartan are two of the most commonly-prescribed high blood pressure medications, however, the side effects may outweigh the benefits. In addition to helping regulate high blood pressure, Valsartan (Diovan) and Losartan (Cozaar) are also used to treat congestive heart failure.

Valsartan recall: global regulatory overview and future challenges

On 5 July 2018 the European Medicines Agency (EMA) reviewed medicines containing valsartan following detection of an impurity, N-nitrosodimethylamine (NDMA), a probable human carcinogen, in medicines from Zhejiang Huahai Pharmaceutical Co Ltd, Linhai, China. Since the batches manufactured from this valsartan-active substance have been administered to many patients, the EMA’s review focused on investigating the levels of NDMA in the products...

‘Please Pay Attention’: Scientist Flagged Heart-Pill Toxins Early On

An expert at the China-based company that made tainted drug ingredients warned in an email of contamination risks a year before a global recall

Hypertension Hot Potato — Anatomy of the Angiotensin-Receptor Blocker Recalls

Although not all products containing valsartan, irbesartan, or losartan that are marketed in the United States have been recalled, the scope of the exposure, the scale of the 20 recalls, and their impact on patient care are staggering...

The Sartan Contamination Story

There's a chemical contamination story in the generic drug industry that just isn't going away. Late last summer, some lots of valsartan were recalled due to detection of N-nitrosodimethylamine (NDMA), and the problem has just continued since then.

Losartan

Losartan increases the urinary flow and increases the excretion of sodium, potassium, chloride, magnesium, uric acid, calcium, and phosphate. Compared to ACE inhibitors, angiotensin II-receptor blockers effectively inhibit the renin-angiotensin system, not affecting the response to bradykinin.[6] For this reason, the non-renin-angiotensin effects, for example, cough and angioedema, are not commonly seen with ARBs.