Midodrine

Is the juice worth the squeeze? Using midodrine - Lauren Igneri

Midodrine
Midodrine

image by: Dysautonomia International

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Midodrine for POTS/dysautonomia

Midodrine works by increasing the tone of our peripheral blood vessels and therefore reduces the likelihood of pooling of blood. It doesn’t really directly affect the heart as such but if there is more blood getting to the heart then that means that every heart beat is more effective and that can have the effect of improving orthostatic tolerance. Interestingly though this can also have an unwanted effect on the bladder. Because of the effect of the agent on tone, the bladder does not stretch as much and therefore bladder emptying is delayed.

So is there any evidence it works? Well yes but the studies are very small and therefore it is not a foregone conclusion by any means.

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 Midodrine for POTS/dysautonomia

Midodrine works by increasing the tone of our peripheral blood vessels and therefore reduces the likelihood of pooling of blood. It doesn’t really directly affect the heart as such but if there is more blood getting to the heart then that means that every heart beat is more effective and that can have the effect of improving orthostatic tolerance. Interestingly though this can also have an unwanted effect on the bladder. Because of the effect of the agent on tone, the bladder does not stretch as much and therefore bladder emptying is delayed.

Midodrine

The recommended dose of Midodrine Hydrochloride Tablets, USP is 10 mg, 3 times daily. Dosing should take place during the daytime hours when the patient needs to be upright, pursuing the activities of daily living.

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