Antiarrhythmics

Rhythm is something you either have or don't have, but when you have it, you have it all over - Elvis Presley

Antiarrhythmics

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Delayed and indirect effects of antiarrhythmic drugs in reducing sudden cardiac death

Antiarrhythmic drugs (AADs) can be used for acute or chronic therapy to prevent ventricular arrhythmias and SCD. Most commonly, AADs are often used in patients with an ICD who have recurrent ICD shocks due to ventricular arrhythmias. Class I AADs are used in patients with a structurally normal heart and are contraindicated in patients with structural heart disease. β-blockers have been demonstrated to be beneficial in preventing mortality and malignant tachyarrhythmias in postmyocardial infarction and congestive heart failure patients, and in patients who have an ICD. Amiodarone has a neutral effect on mortality, while other class III drugs may increase mortality in certain subgroups of patients.

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Last Updated : Sunday, July 24, 2022