This fundamental building block of life will stop your heart – just long enough to be useful - Christina Shenvi MD PhD


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All About Adenosine


Adenosine is one of components of RNA, but given intravenously, it works to terminate SVTs by binding to the AV node’s A1 receptors. This inhibits adenylyl cyclase, ultimately increasing potassium efflux from the cell, causing hyperpolarization, and thereby “blocking” the AV node. This prevents atrial impulses from reaching the ventricles through the AV node, and also blocks re-entrant tachycardias that rely on conduction through the AV node.

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Last Updated : Wednesday, March 9, 2022