Tularemia

Tularemia is a classic zoonosis, capable of being transmitted by aerosol droplets, direct contact, ingestion, or through bites of arthropods — primarily ticks - Dr. Ron Clarke

Tularemia
Tularemia

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Tularemia on the Tube

The Cold War race to use diseases as weapons is driving much of the action this season on FX’s The Americans, the critically acclaimed television drama in which two Soviet intelligence agents pose as a married couple to spy on the American government. The protagonists pick up a most important package from another Russian secret agent working at the CDC: a jar containing a dead rat infected with tularemia. The Soviets are anxious to get the rodent back to the motherland to add to their arsenal.

Tularemia’s relative obscurity left this ardent viewer with a lot of questions about possible plot holes and the history of the disease. As luck would have it, one of the world’s foremost tularemia…

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 Tularemia on the Tube

One of the world’s foremost researchers studying the obscure but highly infectious, potentially fatal disease discusses how it figures into the plot of “The Americans”

CDC

Tularemia is not known to be spread from person to person. People who have tularemia do not need to be isolated. People who have been exposed to the tularemia bacteria should be treated as soon as possible. The disease can be fatal if it is not treated with the right antibiotics.

CIDRAP

In both glandular and ulceroglandular tularemia, organisms enter the skin through the bite of infective arthropods, direct contact with infectious materials (such as contaminated carcasses), or percutaneous inoculation with a sharp object (such as a bone fragment from a contaminated carcass).

MedicineNet

F. tularensis can be freeze-dried and made into a powder which can be aerosolized. This makes it a potential source of bioterrorism similar to anthrax, botulism, or brucellosis because it could be delivered to large numbers of people.

Occupational Safety & Health Administration

Approximately 200 cases of tularemia in humans are reported annually in the United States, mostly in persons living in the south-central and western states. Tularemia is an occupational risk for farmers, foresters, and veterinarians, and is listed by the US Centers for Disease Control and Prevention (CDC) as one of the six category A, or high-priority, biological warfare agents.

Scientists show how tularemia bacteria trick cells to cause disease

Previously, researchers discovered that F. tularensis could inhibit inflammation following infection of immune system cells called macrophages, but they did not understand how it occurred.

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