image by: Ormoc's Only Top Diary
Break-bone fever. Break heart fever. Seven-day fever. They are all names for the painful — often debilitating and sometimes deadly — mosquito-borne disease called dengue fever. Dengue can cause high fever, nausea, rash, body aches, and stiff movements, and can leave patients suffering from depression and fatigue in its wake...
While dengue fever isn’t as deadly as other mosquito-borne viruses — such as Japanese encephalitis, a dengue-related virus found in southern and eastern Asia — large outbreaks can quickly overwhelm health care systems, worsening the toll of other illnesses and medical problems. “It’s one of those rare diseases that impact families, impacts communities, and…
read full article
~1/2 of the world’s population lives in areas with dengue risk.
Dengue is common in popular tourist destinations such as the Caribbean, Puerto Rico, Central and South America, Southeast Asia, the Pacific Islands, and Africa.
A recent study published by the Royal Society indicates that dengue-carrying mosquitoes are expanding their range by an average of 6.5 meters of elevation and have moved polewards by 4.7 km annually.
Warming temperatures and unprecedented flooding have also encouraged the spread of mosquitos well beyond their traditional breeding grounds, bringing dengue fever, malaria and the Zika virus to areas never before threatened by these debilitating illnesses.
The painful disease has been around for centuries but began a dramatic upswing in the 1980s. In the Americas alone, the annual number of cases has boomed from 520,000 in 2003 to 2.3 million in 2013.
Scientists are immunizing mosquitoes against disease with the help of a common microbe.
India is not alone in suffering from dengue. Brazil, for example, endures high rates of infection, and the disease is a threat in much of the rest of South and South-East Asia.
Can genetic modification eliminate a deadly tropical disease?
Researchers at the university are part of a global effort exploring whether a bacterium called Wolbachia can be used to control dengue. Wolbachia occurs naturally in 70 percent of all insects, and it is harmless to humans. But it can block the transmission of dengue by mosquitoes.
Dengue fever, borne by mosquitoes, kills around 20,000 people a year. Oxford-based scientists think they can solve the problem by disrupting breeding in high-risk areas with genetically modified insects. But is that safe?
I didn't buy any souvenirs on my recent trip to the Yucatán. Mostly what they sell visitors to Mérida are hammocks and Guayabera shirts. I took something else home instead-- Dengue fever, an infectious tropical disease transmitted by mosquitoes. It's different from the deadly dengue hemorrhagic fever, which I don't have. The one I have takes a week or two and you're better... or so my doctor says.
The vicious virus has re-established itself in the South, and mosquitoes are carrying it north.
This project completed in July 2017. The Eliminate Dengue project (now known as the World Mosquito Program) is a continuation of research initiated under the FNIH’s Vector-based Control of Transmission: Discovery Research (VCTR) program, which is an extension of the Bill & Melinda Gates Foundation's Grand Challenges in Global Health initiative. Dengue is a disabling and sometimes deadly viral infection that causes high fever, intense muscle pain and bleeding
Zika virus is a flavivirus, similar to dengue. In fact, for people infected with the virus, infection is indistinguishable from dengue using classic antibody tests. This made scientists wonder: could prior infection with Zika cause an antibody-dependent enhancement response following dengue infection or vice versa?
Test in Brazilian city Juazeiro is most successful trial of altered skeeters ever.
The fear that DHF could put a stop to Key West’s endless party is why the local government is proposing something radical: the first trial of genetically modified mosquitoes on US soil.
The virus started with a fever, chills, and headaches. Suddenly my hands & feet erupted with red dots and began to hurt. I was infected with Dengue Fever & didn’t know it.
Immunization can go ahead but affordability in middle-income countries remains an issue.
Since the program began there has been a decrease in the number of dengue cases. While it is too early to claim the decrease is a direct outcome of their efforts, Geana said an entomological count of mosquitoes at the beginning of the work, compared with an upcoming count, will at least show how effective the garbage removal efforts have been in reducing the number of mosquitoes.
Large parts of Europe, West and Central Africa, and South America face the threat of outbreaks of the deadly dengue virus due to climate change and urbanization, according to the first-ever maps of dengue vulnerability published on Tuesday.
Hotez predicts that dengue, chikungunya, and Zika are likely to show up along the US Gulf Coast soon. “On the Gulf Coast, you’ve got the perfect storm of the Aedes aegypti mosquito, the warm subtropical climate, and poverty,” he says. That makes it more likely people will live without window screens and near standing water where mosquitoes can breed. And as the climate warms, mosquitos are only going to move farther and farther north, potentially bringing these diseases with them.
Dengue outbreaks are spreading across the globe thanks to a “perfect storm” of climate change, rapid urbanisation and intercontinental travel, experts have warned.
Scientists bred the mosquitoes. The small insects carry bacteria called Wolbachia that stop the spread of the disease. When these mosquitoes reproduce, they pass on the bacteria and reduce future outbreaks.
Aedes aegypti mosquitoes transmit viruses that are responsible for a significant global public health burden such as Zika, dengue, and yellow fever. Now, researchers found that an Ae. aegypti protein, Argonaute 2, has a key role—via several biological mechanisms—in keeping mosquitoes healthy and active despite these infections. These findings could lead to better methods for reducing the mosquito-to-human transmission of viruses.
Test results indicated that the boy had had dengue fever. And for reasons that are only beginning to be understood, a second infection of the dengue virus is often much worse than the first. A small percentage of those who have already been infected are eight times as likely to develop a potentially deadly form of the disease — dengue shock syndrome — should they ever get it again.
Urbanization, transportation, and climate change are rapidly expanding mosquito habitats. That’s bad news.
Currently, there is one globally approved vaccine, which contains a cocktail that presents four different serotypes chimeric dengue particles, but it is only partly effective and works only on those who have been infected by the dengue virus before.
There are four dengue virus serotypes (DENV-1, DENV-2, DENV-3, and DENV-4), all of which circulate globally. The four dengue virus serotypes are closely related but can be differentiated on serologic tests. Infection with one serotype generally produces long-lived immunity to that serotype, but only provides short-lived protection against infection with other serotypes. For this reason, a person can be infected with DENV as many as four times in their lifetime.
Most dengue patients recover if the infection is detected and treated early.
Heat, hassle, constant staring and culture shock, just another day in India. Until something that up until that point I assumed would never happen did. I caught dengue fever, and it knocked me on my arse so hard I didn’t know what had hit me.
This painful, mosquito-borne virus could spread even more if new innovations can’t scale.
Let´s connect patients, governments, NGOs, doctors, the pharmaceutical industry and other stakeholders wherever they might be in the world.
And let´s work together towards a common goal: to stop dengue.
This map may be used as a guide for the assessment of dengue risk throughout the world. A lack of recent reports for an area does not indicate that no transmission is occurring, particularly in the areas where dengue viruses are known to be endemic.
The World Mosquito Program uses safe and natural bacteria called Wolbachia to prevent the transmission of mosquito-borne viral diseases such as dengue, Zika, chikungunya and yellow fever.
With more than one-third of the world’s population living in areas at risk for infection, dengue virus is a leading cause of illness and death in the tropics and subtropics. As many as 400 million people are infected yearly. Dengue is caused by any one of four related viruses transmitted by mosquitoes. There are not yet any vaccines to prevent infection with dengue virus and the most effective protective measures are those that avoid mosquito bites.
Factors that put you at greater risk of developing dengue fever or a more severe form of the disease include:
•Living or traveling in tropical areas. Being in tropical and subtropical areas increases your risk of exposure to the virus that causes dengue fever. Especially high-risk areas are Southeast Asia, the western Pacific islands, Latin America and the Caribbean.
•Prior infection with a dengue fever virus. Previous infection with a dengue fever virus increases your risk of having severe symptoms if you're infected again.
Symptoms include as severe joint and muscle pain, swollen lymph nodes, headache, fever, exhaustion, and rash. The presence of fever, rash, and headache (the "dengue triad") is characteristic of dengue fever.
Dengue fever is being seen more often in world travelers.
Dengue fever should not be confused with Dengue hemorrhagic fever, which is a separate disease that is caused by the same type of virus, but has much more severe symptoms.
The condition is widespread in areas of the world with a high mosquito population and has been spread by the trade in worn car tyres, which collect water where mosquitoes breed. Typically, dengue occurs in areas that have a combination of:
•a warm and humid climate
•overcrowding and major urban centres
The mosquitoes that spread dengue are rare in England, and cases that develop in the UK occur in travellers who picked up the infection overseas.
•Dr Benjamin Rush (a signatory of the American Declaration of Independence) in Philadelphia coined the name 'breakbone fever' in 1780. This was the first clear description of dengue fever in English. This was during the first simultaneous reported epidemics in Asia, Africa, and North America of 1779-1780.
Severe dengue (also known as Dengue Haemorrhagic Fever) was first recognized in the 1950s during dengue epidemics in the Philippines and Thailand. Today, severe dengue affects most Asian and Latin American countries and has become a leading cause of hospitalization and death among children in these regions.