Warming temperatures and unprecedented flooding have also encouraged the spread of mosquitos well beyond their traditional breeding grounds, bringing dengue fever, malaria and the Zika virus to areas never before threatened by these debilitating illnesses - Jacqueline Houtman PhD


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Half the world is at risk of dengue. Why is there no universal way to prevent it?

Break-bone fever. Break heart fever. Seven-day fever. They are all names for the painful — often debilitating and sometimes deadly — mosquito-borne disease called dengue fever. Dengue can cause high fever, nausea, rash, body aches, and stiff movements, and can leave patients suffering from depression and fatigue in its wake...

While dengue fever isn’t as deadly as other mosquito-borne viruses — such as Japanese encephalitis, a dengue-related virus found in southern and eastern Asia — large outbreaks can quickly overwhelm health care systems, worsening the toll of other illnesses and medical problems. “It’s one of those rare diseases that impact families, impacts communities, and…

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 Half the world is at risk of dengue. Why is there no universal way to prevent it?

This painful, mosquito-borne virus could spread even more if new innovations can’t scale.

Break Dengue

Let´s connect patients, governments, NGOs, doctors, the pharmaceutical industry and other stakeholders wherever they might be in the world. And let´s work together towards a common goal: to stop dengue.


This map may be used as a guide for the assessment of dengue risk throughout the world. A lack of recent reports for an area does not indicate that no transmission is occurring, particularly in the areas where dengue viruses are known to be endemic.

World Mosquito Program

The World Mosquito Program uses safe and natural bacteria called Wolbachia to prevent the transmission of mosquito-borne viral diseases such as dengue, Zika, chikungunya and yellow fever.


With more than one-third of the world’s population living in areas at risk for infection, dengue virus is a leading cause of illness and death in the tropics and subtropics. As many as 400 million people are infected yearly. Dengue is caused by any one of four related viruses transmitted by mosquitoes. There are not yet any vaccines to prevent infection with dengue virus and the most effective protective measures are those that avoid mosquito bites.


Factors that put you at greater risk of developing dengue fever or a more severe form of the disease include: •Living or traveling in tropical areas. Being in tropical and subtropical areas increases your risk of exposure to the virus that causes dengue fever. Especially high-risk areas are Southeast Asia, the western Pacific islands, Latin America and the Caribbean. •Prior infection with a dengue fever virus. Previous infection with a dengue fever virus increases your risk of having severe symptoms if you're infected again.


Symptoms include as severe joint and muscle pain, swollen lymph nodes, headache, fever, exhaustion, and rash. The presence of fever, rash, and headache (the "dengue triad") is characteristic of dengue fever.


Dengue fever is being seen more often in world travelers. Dengue fever should not be confused with Dengue hemorrhagic fever, which is a separate disease that is caused by the same type of virus, but has much more severe symptoms.


The condition is widespread in areas of the world with a high mosquito population and has been spread by the trade in worn car tyres, which collect water where mosquitoes breed. Typically, dengue occurs in areas that have a combination of: •a warm and humid climate •overcrowding and major urban centres The mosquitoes that spread dengue are rare in England, and cases that develop in the UK occur in travellers who picked up the infection overseas.


•Dr Benjamin Rush (a signatory of the American Declaration of Independence) in Philadelphia coined the name 'breakbone fever' in 1780. This was the first clear description of dengue fever in English. This was during the first simultaneous reported epidemics in Asia, Africa, and North America of 1779-1780.


Severe dengue (also known as Dengue Haemorrhagic Fever) was first recognized in the 1950s during dengue epidemics in the Philippines and Thailand. Today, severe dengue affects most Asian and Latin American countries and has become a leading cause of hospitalization and death among children in these regions.

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