Antiprotozoal Drugs

Human protozoal infections are ubiquitous and occur worldwide. In many cases, antiprotozoal agents currently in use predate the modern antibiotic era - M Khaw

Antiprotozoal Drugs
Antiprotozoal Drugs

image by: All about Microbiology

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Challenges and Promises for Obtaining New Antiprotozoal Drugs: What’s Going Wrong?

Infections by protozoa can cause some of the most serious human diseases, particularly in tropical regions. However, the number of available drugs used to treat such diseases tends to be limited with relatively high toxicity, and the vast majority of such drugs were developed in the 1920s to 1970s. The development of antiprotozoal drugs has been hindered owing in part to: (1) the highly complicated life cycles of such organisms and their ability to avoid innate immune defences; (2) challenges associated with culturing such organisms particularly in different phases of their growth and amplification; and (3) a lack of investment in biomedical research aimed at developing treatments for tropical…

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 Challenges and Promises for Obtaining New Antiprotozoal Drugs: What’s Going Wrong?

Indeed, only three new drugs have entered into clinical trials in recent times, highlighting the tremendous gap in knowledge that should be bridged to more effectively treat protozoal infections.


Substances that are destructive to protozoans.

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