Erythema Multiforme

If it involves more than the extremities, think twice about calling it erythema multiforme. Think worse first! Look for the mucosal membrane involvement closely - Sean Fox

Erythema Multiforme
Erythema Multiforme

image by: غسان للكتب الطبية - Ghassan For Medical Books

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Erythema Multiforme in Children

Parents pay a lot of attention to the skin of their child and, certainly, the skin exam is a valuable tool for the vigilant clinician (ex, Cap Refill, Petechiae below Nipple Line, Leukemia, RMSF). That being said, the majority of pediatric rashes... that present to the ED are often met with a combination of disdain and fear: “This looks like nothing, but is it something?” or “This looks awful, but is it a big deal?”

One of the concerning characteristics is the target lesion, but not all target lesions are created equal.

Erythema Multiforme: Basics

Erythema multiforme is the skin manifestations of an acute immune-mediated reaction. The immune-mediated…

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Resources

 Erythema Multiforme in Children

The majority of pediatric rashes that present to the ED are often met with a combination of disdain and fear: “This looks like nothing, but is it something?” or “This looks awful, but is it a big deal?” One of the concerning characteristics is the target lesion, but not all target lesions are created equal. Let us take a minute to digest a morsel on Erythema Multiforme...

This Lupus Life

A skin disease characterized by papular or vesicular lesions and reddening or discoloration of the skin often in concentric zones about the lesions

DermNet New Zealand

Erythema multiforme is a hypersensitivity reaction usually triggered by infections, most commonly herpes simplex virus (HSV). It presents with a skin eruption characterised by a typical target lesion. There may be mucous membrane involvement. It is acute and self-limiting, usually resolving without complications. Erythema multiforme is divided into major and minor forms and is now regarded as distinct from Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

NORD

Onset of erythema multiforme is usually sudden in an otherwise healthy individual. Red spots (macules or papules), or ridges (wheals), and sometimes blisters appear on the tops of the hands and forearms. Other areas of involvement may include the face, neck, palms, soles of feet, legs, and trunk.

Patient

Erythema multiforme (EM) is a skin condition considered to be a hypersensitivity reaction to infections or drugs.[1]It presents as a dermatological eruption featuring iris or target lesions, although other forms of skin lesion can occur - hence the name. It is usually an acute, self-limiting disease that affects the skin. Mucous membranes, however, are affected little, if at all. (EM was previously described as having minor and major forms. The major form - more serious and with more extensive involvement of both skin and mucosa - is now known as Stevens-Johnson syndrome (SJS).)

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