Monoclonal Antibodies

It is the most important achievement of my life - Dr. Jean-Jacques Muyembe Tamfum

Monoclonal Antibodies

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“Blood is an unusual fluid”: The therapeutic antibody revolution

Replacing missing or faulty human hormones with their recombinant equivalents is a relatively straightforward way to treat disease. But by the mid-1980s, scientists were beginning to think about how they could exploit a more mysterious and unpredictable class of human proteins, antibodies.

Antibodies are small proteins produced by B cells which form part of our immune systems. They recognise and bind to foreign material like viruses, bacteria, toxins, and even rogue cells within our own bodies. Each antibody consists of four protein chains arranged in a Y shape. They have constant regions and variable regions of around 110-130 amino acids on the arms of the Y that allow the antibody…

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Last Updated : Sunday, September 12, 2021