Ethylene Glycol

The parent compounds for ethylene glycol and methanol are innocuous and the metabolites are toxic - Michelle Lin MD

Ethylene Glycol

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Lactate gap in ethylene glycol toxicity

When making a decision about urgent dialysis it is important to have an much information as quickly as possible. In suspected ethylene glycol toxicity time is of the essence. Waiting 3-4 hours or more for the ethylene glycol level to come back can be deleterious to the patient. Often times we are left to make the decision to begin dialysis or therapy based upon a high degree of suspicion from the available laboratory data and patient circumstances. During conference recently I heard of another pearl that could help in determining if ethylene glycol was ingested.

This is termed the lactate gap. Essentially this is the difference in values obtained from 2 different analyzer methods.…

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Last Updated : Sunday, November 27, 2022