Neurodegenerative Disease

The key to the future in an aging society is not found in increasing just our life span; we need to increase our health span at the same time - Chuck Norris

Neurodegenerative Disease

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The neural economics of brain aging

Neurodegenerative diseases are chronic, progressive processes that present almost exclusively in late life. They are in common characterized by the accumulation of various forms of protein aggregates accompanied by neurodegeneration. These neuropathological hallmarks herald pathogenic cascades from the molecular to systems level encompassing proteostatic stress, neuroinflammation, synaptic loss, neuronal dysfunction and network failure with genetic studies demonstrating that accumulation of the aggregates themselves are indeed the primary etiological driver. These processes evolve to distribute across the brain in characteristic patterns, causing commensurate patterns of functional decline…

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 The neural economics of brain aging

Despite remarkable advances, research into neurodegeneration and Alzheimer Disease (AD) has nonetheless been dominated by inconsistent and conflicting theory. Basic questions regarding how and why the brain changes over time remain unanswered.

Center for Neurodegenerative Disease Research

The mission of the Center for Neurodegenerative Disease Research (CNDR) is to promote and conduct multidisciplinary clinical and basic research to increase the understanding of the causes and mechanisms leading to brain dysfunction and degeneration in neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Lewy body dementia (LBD), Frontotemporal degeneration (FTD), Amyotrophic lateral sclerosis (ALS), Primary lateral sclerosis (PLS), Motor neuron disease (MND), and related disorders that occur increasingly with advancing age.

Center for Translational Research in Neurodegenerative Disease

The University of Florida's Center for Translational Research in Neurodegenerative Disease, known as the CTRND, is a state-of-the-art, multidisciplinary research center focused on the discovery, development and evaluation of future treatments and diagnostics for degenerative central nervous system conditions including Alzheimer's disease, Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Lobar Degeneration (FTLD), Parkinson's disease and stroke.

Harvard NeuroDiscovery Center

Established in 2001, the Harvard NeuroDiscovery Center is a pioneering biomedical research group focused on ending suffering from neurodegenerative diseases. By drawing on the intellectual strength and proven capability of the Harvard medical community and colleagues throughout the world, the NeuroDiscovery Center has developed a unique approach to understanding and treating these devastating diseases.

National Institute of Environmental Health Sciences

Neurodegenerative diseases affect millions of people worldwide. Alzheimer’s disease and Parkinson’s disease are the most common neurodegenerative diseases.

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